Global Genetic Analysis
نویسندگان
چکیده
منابع مشابه
Global genetic analysis.
The introduction of molecular markers in genetic analysis has revolutionized medicine. These molecular markers are genetic variations associated with a predisposition to common diseases and individual variations in drug responses. Identification and genotyping a vast number of genetic polymorphisms in large populations are increasingly important for disease gene identification, pharmacogenetics...
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Computer-assisted methods have become very important in analyzing biosequence data. However, most of the current methods are limited to nding motifs only. Genes can be regulated in many ways, including combinations of regulatory elements. This research is aimed at combinatorial motif analysis and hypothesis generation. A genome-wide gene expression analysis demonstrated the value of the studies...
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Artificial genetic circuits are becoming important tools for controlling cellular behavior and studying molecular biosystems. To genetically optimize the properties of complex circuits in a practically feasible fashion, it is necessary to identify the best genes and/or their regulatory components as mutation targets to avoid the mutation experiments being wasted on ineffective regions, but this...
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Aspergillus fumigatus is a ubiquitous opportunistic fungal pathogen capable of causing invasive aspergillosis, a globally distributed disease with a mortality rate of up to 90% in high-risk populations. Effective control and prevention of this disease require a thorough understanding of its epidemiology. However, despite significant efforts, the global molecular epidemiology of A. fumigatus rem...
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BACKGROUND Understanding gene function and genetic relationships is fundamental to our efforts to better understand biological systems. Previous studies systematically describing genetic interactions on a global scale have either focused on core biological processes in protozoans or surveyed catastrophic interactions in metazoans. Here, we describe a reliable high-throughput approach capable of...
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ژورنال
عنوان ژورنال: BMB Reports
سال: 2004
ISSN: 1976-6696
DOI: 10.5483/bmbrep.2004.37.1.011